| Wake Forest University Baptist Medical Center | | Winstonsalem, NC | Local | 5 | 2024 | $41,782,859 |
| Alzheimers Disease and Related Disorders Association Inc | | Chicago, IL | National | 6 | 2024 | $40,231,146 |
| Duke Endowment | | Charlotte, NC | Local | 6 | 2024 | $7,092,758 |
| Atrium Health Foundation | | Charlotte, NC | Local | 2 | 2024 | $2,159,246 |
| Lettie Pate Whitehead Foundation Inc | | Atlanta, GA | National | 5 | 2024 | $1,700,000 |
| Yale University | | New Haven, CT | National | 2 | 2024 | $1,429,855 |
| Broad Institute Inc | | Cambridge, MA | Local | 8 | 2024 | $1,181,782 |
| American Diabetes Association Inc | | Arlington, VA | Local | 3 | 2024 | $1,094,959 |
| Trustees of Tufts College | | Medford, MA | National | 6 | 2024 | $894,327 |
| Doris Duke Charitable Foundation Inc | | New York, NY | National | 2 | 2024 | $660,000 |
| Lupus Research Alliance Inc | | New York, NY | National | 5 | 2024 | $423,000 |
| Emory University | | Atlanta, GA | Local | 4 | 2024 | $302,373 |
| American Medical Association | | Chicago, IL | National | 5 | 2024 | $260,000 |
| Cannon Family Charitable Trust | | Raleigh, NC | Local | 1 | 2024 | $250,000 |
| St Baldricks Foundation Inc | | Monrovia, CA | National | 5 | 2024 | $249,933 |
| Ao North America Inc | | Wayne, PA | National | 5 | 2024 | $235,000 |
| Alzheimers Disease Research Foundation | | Wellesley Hls, MA | Local | 1 | 2024 | $201,250 |
| National Foundation of Emergency Medicine Inc | | Baltimore, MD | National | 4 | 2024 | $175,000 |
| Commonwealth Fund | | New York, NY | National | 4 | 2024 | $117,701 |
| Emergency Medicine Foundation | | Irving, TX | National | 2 | 2024 | $109,890 |
| American Nurses Foundation Inc | | Silver Spring, MD | National | 2 | 2024 | $101,019 |
| Cannon Foundation Inc | | Concord, NC | Local | 1 | 2024 | $100,000 |
| Amyotrophic Lateral Sclerosis Assn | | Saint Paul, MN | National | 3 | 2024 | $65,000 |
| Richard Adams Char Fdn Tr | | Saint Louis, MO | Local | 3 | 2024 | $54,000 |
| Dudley and Constance Godfrey Foundation Inc | | New York, NY | Local | 4 | 2024 | $37,500 |
| American Academy of Orthopedic Surgeons | | Rosemont, IL | Local | 2 | 2024 | $20,000 |
| James IV Association of Surgeons | | Palo Alto, CA | Local | 1 | 2024 | $15,000 |
| Childs Play | | Seattle, WA | National | 1 | 2024 | $3,500 |
| Cystic Fibrosis Foundation | | Bethesda, MD | National | 6 | 2023 | $1,664,073 |
| George Washington University | | Ashburn, VA | National | 6 | 2023 | $1,383,692 |
| Errett Fisher Foundation | | Santa Barbara, CA | Local | 4 | 2023 | $620,260 |
| Beth Israel Deaconess Medical Center Inc | | Boston, MA | Local | 2 | 2023 | $302,310 |
| Trustees of Boston University | | Boston, MA | National | 2 | 2023 | $212,820 |
| Public Health Institute | | Oakland, CA | Local | 3 | 2023 | $196,638 |
| Laura and John Arnold Foundation | | Houston, TX | National | 1 | 2023 | $162,756 |
| Childhood Arthritis & Rheumatology Research Alliance | | Washington, DC | National | 1 | 2023 | $150,000 |
| High Point Regional Health Foundation | | High Point, NC | Local | 1 | 2023 | $110,381 |
| Alliance Nctn Foundation | | Chicago, IL | National | 4 | 2023 | $78,850 |
| National Organization for Rare Disorders Inc | | Danbury, CT | National | 2 | 2023 | $75,000 |
| Truist Foundation Inc | | Orlando, FL | National | 1 | 2023 | $25,000 |
| Johns Hopkins University | | Baltimore, MD | National | 5 | 2022 | $8,791,082 |
| Breakthrough T1D | | New York, NY | National | 2 | 2022 | $499,998 |
| American Federation for Aging | | New York, NY | National | 1 | 2022 | $375,000 |
| Northwestern University | | Evanston, IL | National | 6 | 2022 | $353,016 |
| Melanoma Research Foundation | | Washington, DC | National | 1 | 2022 | $199,002 |
| Center for Orthopaedic Trauma Advancement | | Rosemont, IL | National | 5 | 2022 | $120,000 |
| Boston Medical Center Corporation | | Boston, MA | Local | 1 | 2022 | $87,411 |
| Association of University Radiologists | | Warrenville, IL | National | 1 | 2022 | $70,000 |
| Alliance for Clinical Trials in Oncology Foundation | | Chicago, IL | National | 4 | 2022 | $64,128 |
| National Alliance for Research on Schizophrenia and Depression Inc | | New York, NY | National | 1 | 2022 | $35,000 |
| The Hope Foundation | | Ann Arbor, MI | National | 2 | 2022 | $32,678 |
| American Association for the Surgery of Trauma | | Chicago, IL | National | 1 | 2022 | $25,000 |
| Muscular Dystrophy Association | | Chicago, IL | National | 1 | 2022 | $25,000 |
| American Association of Hip & Knee Surgeons | | Rosemont, IL | National | 1 | 2022 | $20,000 |
| Arthroscopy Association of North America Inc | | Rosemont, IL | National | 2 | 2022 | $12,624 |
| Moses Cone-Wesley Long Community Health Foundation Inc | | Greensboro, NC | Local | 5 | 2021 | $593,600 |
| The Childrens Hospital of Philadelphia | | Philadelphia, PA | National | 3 | 2021 | $399,875 |
| Susan G Komen Breast Cancer Foundation | | Dallas, TX | National | 3 | 2021 | $390,000 |
| Lisa Dean Moseley Foundation | | Rockland, DE | National | 2 | 2021 | $374,536 |
| Cancer Research America Nfcr Inc | | Rockville, MD | Local | 4 | 2021 | $283,606 |
| Fred Hutchinson Cancer Research Center | | | — | 1 | 2021 | $234,261 |
| Oxalosis and Hyperoxaluria Foundation | | New Paltz, NY | National | 1 | 2021 | $200,000 |
| Wake Forest University Development Foundation | | Winston Salem, NC | Local | 1 | 2021 | $171,100 |
| Barth Syndrome Foundation Inc | | Larchmont, NY | National | 1 | 2021 | $100,000 |
| Foundation for Womens Cancer | | Chicago, IL | National | 1 | 2021 | $50,000 |
| American Glaucome Society Inc | | San Francisco, CA | Local | 1 | 2021 | $10,000 |
| Fred Hutchinson Cancer Center | | Seattle, WA | National | 1 | 2021 | $8,485 |
| Institute for Advanced Clinical Trials for Children | | | National | 1 | 2021 | $7,500 |
| Wsp Foundation Inc | | New York, NY | National | 1 | 2021 | $5,000 |
| The Fullerton Foundation Inc | | Gaffney, SC | Local | 1 | 2021 | $2,000 |
| Michael J Fox Foundation for Parkinsons Research | | New York, NY | National | 1 | 2020 | $481,949 |
| International Myeloma Foundation | | Studio City, CA | National | 2 | 2020 | $133,332 |
| American Academy of Clinical Toxicology | | East Dundee, IL | — | 1 | 2020 | $46,988 |
| Appendix Cancer Pseudomyxoma Peritonei Research Foundation | | Springfield, PA | — | 1 | 2020 | $20,000 |
| North Carolina Baptist Hospital | | Winstonsalem, NC | Local | 1 | 2020 | $17,549 |
| Society of Family Planning Research Fund | | | — | 1 | 2020 | $15,000 |
| John a Hartford Foundation | | New York, NY | National | 1 | 2020 | $8,250 |
| Black-Brogan Foundation | | New York, NY | Local | 1 | 2019 | $100,000 |
| Idsa Education and Research Foundation | | Arlington, VA | National | 1 | 2019 | $100,000 |
| Lung Cancer Initiative | | Raleigh, NC | Local | 2 | 2019 | $75,000 |
| Copd Foundation Inc | | Coral Gables, FL | — | 1 | 2019 | $74,688 |
| Alternatives for Research and Development Foundation | | Jenkintown, PA | National | 1 | 2019 | $40,000 |
| Orthopedic Trauma Association Inc | | Schaumburg, IL | National | 1 | 2019 | $37,122 |
| Hemophilia of Georgia Inc | | Sandy Springs, GA | Local | 2 | 2019 | $31,997 |
| Forsyth Medical Center Foundation | | Winston Salem, NC | Local | 1 | 2019 | $11,275 |
| Institute for Clinical Research Inc | | Washington, DC | National | 1 | 2019 | $6,510 |
| Orthopaedic Research and Education Foundation | | Rosemont, IL | National | 1 | 2019 | $5,000 |
| De Beaumont Foundation Inc | | Bethesda, MD | National | 1 | 2018 | $350,000 |
| American Diabetes Association Research Foundation Inc | | | — | 1 | 2018 | $197,953 |
| Forsyth Memorial Hospital Inc | | Winston Salem, NC | Local | 1 | 2018 | $150,000 |
| Lung Cancer Research Foundation | | Philadelphia, PA | National | 1 | 2018 | $149,948 |
| Childress Institute for Pediatric Trauma | | Winston Salem, NC | — | 1 | 2018 | $105,000 |
| South Carolina Research Foundation | | Columbia, SC | — | 2 | 2018 | $100,000 |
| Health Sciences South Carolina | | Columbia, SC | — | 2 | 2018 | $100,000 |
| California Eastern Star Foundation | | Yorba Linda, CA | Local | 1 | 2018 | $36,381 |
| John Wayne Cancer Foundation | | Costa Mesa, CA | National | 1 | 2018 | $25,000 |
| Benaroya Research Institute at Virginia Mason | | Seattle, WA | National | 1 | 2018 | $13,504 |
| Make a Difference Fund Inc | | Rocky Mount, NC | Local | 1 | 2018 | $5,000 |
| American Academy of Pediatrics Inc | | Itasca, IL | National | 1 | 2017 | $40,000 |
| University of Miami | | Coral Gables, FL | National | 1 | 2017 | $11,606 |