| Pediatric Endowment Fund Inc | | Louisville, KY | Local | 4 | 2024 | $3,531,609 |
| University of Pittsburgh | | Pittsburgh, PA | National | 7 | 2024 | $2,087,178 |
| University of Southern California | | Los Angeles, CA | National | 2 | 2024 | $1,766,878 |
| Emory University | | Atlanta, GA | Local | 4 | 2024 | $1,362,247 |
| Robert Wood Johnson Foundation | | Princeton, NJ | National | 1 | 2024 | $1,155,836 |
| Johns Hopkins University | | Baltimore, MD | National | 3 | 2024 | $664,998 |
| Vanderbilt University | | Nashville, TN | Local | 7 | 2024 | $608,884 |
| Amplify Louisville Inc | | Louisville, KY | Local | 3 | 2024 | $455,349 |
| University of Miami | | Coral Gables, FL | National | 4 | 2024 | $424,873 |
| The Administrators of the Tulane Educational Fund | | New Orleans, LA | National | 2 | 2024 | $301,562 |
| Knights Templar Eye Foundation Inc | | Flower Mound, TX | National | 3 | 2024 | $270,000 |
| National Eating Disorders Association | | White Plains, NY | National | 1 | 2024 | $125,000 |
| Wings for Life USA - Spinal Cord Research Foundation Inc | | Santa Monica, CA | National | 1 | 2024 | $108,400 |
| Neurosurgery Research and Education Foundation | | Rolling Meadows, IL | National | 2 | 2024 | $100,000 |
| National Science Teaching Association | | Mclean, VA | Local | 6 | 2024 | $78,034 |
| Apgar Foundation Inc | | Indianapolis, IN | National | 3 | 2024 | $75,000 |
| Childrens Oncology Group Foundation | | Philadelphia, PA | National | 3 | 2024 | $71,550 |
| The Cci Research Foundation | | | National | 2 | 2024 | $52,500 |
| Child Neurology Education and Research Foundation | | Hamilton, OH | National | 2 | 2024 | $50,000 |
| Mayo Clinic | | Rochester, MN | National | 1 | 2024 | $42,144 |
| Northeastern University | | Boston, MA | National | 1 | 2024 | $34,894 |
| American Association of Hip & Knee Surgeons | | Rosemont, IL | National | 2 | 2024 | $33,800 |
| Temple University-of the Commonwealth System of Higher Educ | | Philadelphia, PA | National | 2 | 2024 | $29,769 |
| Engineering Information Foundation Inc | | New York, NY | National | 1 | 2024 | $25,000 |
| West Virginia University Research Corporation | | Morgantown, WV | National | 1 | 2024 | $13,057 |
| Oral and Maxillofacial Surgery Foundation | | Rosemont, IL | Local | 1 | 2024 | $12,500 |
| Families Rising | | Saint Paul, MN | Local | 1 | 2024 | $11,605 |
| William Townsend Porter Foundation Inc | | Boston, MA | Local | 1 | 2024 | $10,000 |
| Great Meadows Foundation Inc | | Louisville, KY | Local | 1 | 2024 | $1,700 |
| Childrens Hospital Foundation | | Louisville, KY | Local | 6 | 2023 | $3,300,503 |
| Cystic Fibrosis Foundation | | Bethesda, MD | National | 6 | 2023 | $2,147,625 |
| American Lung Association | | Chicago, IL | National | 3 | 2023 | $575,000 |
| American Foundation for Suicide Prevention | | New York, NY | National | 3 | 2023 | $149,890 |
| Drexel University | | Philadelphia, PA | National | 3 | 2023 | $118,772 |
| Muscular Dystrophy Association | | Chicago, IL | National | 6 | 2023 | $108,675 |
| Association of Universities for | | Tucson, AZ | National | 2 | 2023 | $68,025 |
| Charles Koch Foundation | | Arlington, VA | National | 4 | 2023 | $52,357 |
| Smith Richardson Foundation Inc | | Greensboro, NC | Local | 1 | 2023 | $25,000 |
| Society of Cardiovascular Anesthesiologists Inc | | East Dundee, IL | National | 1 | 2023 | $15,000 |
| Christopher Reeve Foundation a New Jersey Nonprofit Corporation | | Short Hills, NJ | National | 5 | 2022 | $4,156,810 |
| Williams Syndrome Association Inc | | Newark, NJ | — | 1 | 2022 | $300,000 |
| Alzheimers Disease and Related Disorders Association Inc | | Chicago, IL | National | 1 | 2022 | $199,857 |
| Seattle Childrens Hospital | | Seattle, WA | National | 3 | 2022 | $81,559 |
| William T Grant Foundation Inc | | New York, NY | National | 2 | 2022 | $49,985 |
| Ndri USA Inc | | New York, NY | Local | 1 | 2022 | $9,718 |
| Rockefeller Foundation | | New York, NY | Local | 1 | 2021 | $1,000,000 |
| Ecmc Foundation | | Minneapolis, MN | National | 1 | 2021 | $130,494 |
| American Academy of Pediatrics Inc | | Itasca, IL | National | 1 | 2021 | $35,000 |
| Society of Toxicology | | Reston, VA | National | 1 | 2021 | $10,000 |
| Legacy Foundation of Kentuckiana Inc | | Phoenix, AZ | Local | 1 | 2021 | $9,450 |
| Institute for Advanced Clinical Trials for Children | | | National | 1 | 2021 | $7,500 |
| Jewish Heritage Fund for Excellence Inc | | Louisville, KY | Local | 2 | 2020 | $2,540,350 |
| National Harm Reduction Coalition | | New York, NY | Local | 1 | 2020 | $100,000 |
| Baptist Healthcare System Inc | | Louisville, KY | Local | 2 | 2020 | $55,000 |
| Spencer Foundation | | Chicago, IL | National | 1 | 2020 | $49,983 |
| Mt Cuba Astronomical Foundation | | Wilmington, DE | Local | 1 | 2020 | $41,137 |
| Simons Foundation Inc | | New York, NY | National | 1 | 2020 | $16,800 |
| Vanderbilt University Medical Center | | Nashville, TN | National | 3 | 2019 | $558,205 |
| Norton Healthcare Inc | | Louisville, KY | Local | 1 | 2019 | $300,000 |
| Catholic Charities of Louisville Inc | | Louisville, KY | Local | 3 | 2019 | $102,986 |
| The Community Foundation of Louisville Corporate Depository in | | Louisville, KY | Local | 1 | 2019 | $50,000 |
| United States Endowment Forforestry and Communities Inc | | Greenville, SC | National | 1 | 2019 | $44,009 |
| Jewish Hospital & St Marys Healthcare Inc | | Phoenix, AZ | — | 1 | 2019 | $17,505 |
| Alfred P Sloan Foundation | | New York, NY | National | 1 | 2019 | $15,350 |
| American Speech-Language-Hearing Foundation | | Rockville, MD | National | 1 | 2019 | $10,000 |
| University of Chicago | | Chicago, IL | National | 2 | 2018 | $831,596 |
| American Diabetes Association Research Foundation Inc | | | — | 1 | 2018 | $372,655 |
| Norton Healthcare Foundation Inc | | Louisville, KY | Local | 1 | 2018 | $310,762 |
| Gordon E and Betty I Moore Foundation | | Palo Alto, CA | National | 1 | 2018 | $92,755 |
| With Foundation | | San Mateo, CA | National | 1 | 2018 | $50,000 |
| University Health Care Inc | | Louisville, KY | — | 1 | 2018 | $48,602 |
| Association of Professional Chaplains Inc | | Hoffman Est, IL | — | 1 | 2018 | $30,000 |
| Georgetown University | | Washington, DC | National | 1 | 2018 | $29,104 |
| All Childrens Research Institute Inc | | St Petersburg, FL | Local | 1 | 2018 | $9,350 |
| Distilled Spirits Council of the United States Inc | | Washington, DC | Local | 1 | 2018 | $8,000 |
| University of Notre Dame Du Lac | | Notre Dame, IN | National | 1 | 2018 | $7,029 |
| University of Kansas Medical Center Research Institute | | Kansas City, KS | Local | 1 | 2017 | $44,746 |
| Hansjorg Wyss Institute for Biologically Inspired Engineering | | Boston, MA | Local | 1 | 2017 | $38,346 |
| University Medical Center Inc | | Louisville, KY | — | 1 | 2017 | $22,220 |